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NHLBI Proteomics Administrative and Coordination Center

UCLA Proteomics Center - Global Proteomic Initiative of Cardiovascular Medicine: Peipei Ping, Ph.D.

UCLA Proteomics Center Global Proteomic Initiative of Cardiovascular Medicine


Peipei Ping, Ph.D., FAHA, FISHR
Professor, Physiology and Medicine/Cardiology
Director, NHLBI Proteomics Center at UCLA

The primary goal of our Center is to drive technological innovations that are specifically tailored to answer long-standing questions in cardiovascular medicine. Through concerted analysis of animal models and human tissues samples, our Center studies will propel translational medicine forward.



The Key Investigators

John Yates III, Co-Director jyates@scripps.edu
Rolf Apweiler, Project Leader apweiler@ebi.ac.uk
Mathias Uhlen, Project Leader
Huilong Duan, Project Leader
Joshua LaBaer, Project Leader
Mario Deng, Project Leader
James N. Weiss, Investigator jweiss@mednet.ucla.edu
Nobel Zong, Investigator
David Liem, Investigator
Henning Hermjakob, Investigator
Jake Lusis, Investigator
Jacob Odeberg, Investigator
Julian Whitelegge, Investigator

Selected Recent Publications

Metabolic Labeling Reveals Proteome Dynamics of Mouse Mitochondria. Kim TY, Wang D, Kim AK, Lau E, Lin AJ, Liem DA, Zhang J, Zong NC, Lam MP, Ping P. Mol Cell Proteomics. 2012 Aug 21. [Epub ahead of print]. PMID: 22915825

ABCC6 Localizes to the Mitochondria-Associated Membrane. Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, Lusis AJ. Circ Res. 2012 Jul 17. [Epub ahead of print]

Substrate- and isoform-specific proteome stability in normal and stressed cardiac mitochondria. Lau E, Wang D, Zhang J, Yu H, Lam MP, Liang X, Zong N, Kim TY, Ping P. Circ Res. 2012;110:1174-8. PMID:2245618

Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria. Deng N, Zhang J, Zong C, Wang Y, Lu H, Yang P, Wang W, Young GW, Wang Y, Korge P, Lotz C, Doran P, Liem DA, Apweiler R, Weiss JN, Duan H, Ping P. Mol Cell Proteomics. 2011;10:M110.000117. PMID:20495213

Dasty3, a web framework for das. Villaveces JM, Jimenez RC, Garcia LJ, Salazar GA, Gel B, Mulder N, Martin M, Garcia A, Hermjakob H. Bioinformatics. 2011;27:2616-2617. PMID:21798964

Toward objective evaluation of proteomic algorithms. Yates JR, 3rd, Park SK, Delahunty CM, Xu T, Savas JN, Cociorva D, Carvalho PC. Nature Methods. 2012;9:455-456. PMID:22509746

An MRM-based workflow for quantifying cardiac mitochondrial protein phosphorylation in murine and human tissue. Lam MP, Scruggs SB, Kim TY, Zong C, Lau E, Wang D, Ryan CM, Faull KF, Ping P. Journal of Proteomics. 2012; Feb 22.

Single-step inline hydroxyapatite enrichment facilitates identification and quantitation of phosphopeptides from mass-limited proteomes with MudPIT. Fonslow BR, Niessen SM, Singh M, Wong CC, Xu T, Carvalho PC, Choi J, Park SK, Yates JR 3rd. Journal of Proteome Research. 2012;11(5):2697-709.

Towards a knowledge-based Human Protein Atlas. Uhlen M, Oksvold P, Fagerberg L, Lundberg E, Jonasson K, Forsberg M, Zwahlen M, Kampf C, Wester K, Hober S, Wernerus H, Björling L, Ponten F. Nat Biotechnol. 2010 Dec;28(12):1248-50. PMID:21139605

Antibody-based protein profiling of the human chromosome 21. Uhlén M, Oksvold P, Älgenäs C, Hamsten C, Fagerberg L, Klevebring D, Lundberg E, Odeberg J, Pontén F, Kondo T, Sivertsson Å. Mol Cell Proteomics. 2012;11:M111.013458. PMID:2204263
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